Thermo Fisher Scientific ZIP12 Polyclonal Antibody
인간 SLC39A12(ZIP12) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 최적화됨. Affinity chromatography로 정제되었으며, 0.5 mg/mL 농도의 액상 형태. 장기 보관 시 -20°C에서 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human SLC39A12 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884299 |
Product Specific Information
Immunogen sequence:
MCFRTKLSVS WVPLFLLLSR VFSTETDKPS AQDSRSRGSS GQPADLLQVL
- For short term use, store at 2–8°C up to 1 week.
- For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Predicted homology: Cow 77%, Horse 85%, Human 100%
Target Information
The zinc transporter ZIP12 (SLC39A12) is a member of the divalent ion transporter family. Zinc is essential for cellular growth, development, and differentiation. The zinc transporter family is divided into four subfamilies: I, II, LIV-1, and gufA. ZIP12, a multipass membrane protein of the LIV-1 subfamily, shows increased expression during airway inflammation and asthma, suggesting a role in zinc uptake and inflammation reduction. Lower brain zinc levels and ZIP12 mutations have been observed in some schizophrenia patients, indicating potential involvement in the disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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