Thermo Fisher Scientific E2F3 Monoclonal Antibody (3E2F04 (PG37))

Applications

Tested Dilution

Publications

Western Blot (WB)

2-3 µg/mL

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Immunohistochemistry (IHC)

-

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Immunohistochemistry (Paraffin) (IHC (P))

-

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ChIP assay (ChIP)

2.5 µg/1x10^6 cells

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Gel Shift (GS)

1 mg/mL

-

Product Specifications

Published species

Human, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

3E2F04 (PG37)

Immunogen

Recombinant human E2F-3 protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10987485

Product Specific Information

MA5-11319 targets E2F-3 Transcription Factor in GS and IF applications and shows reactivity with Human samples.

The MA5-11319 immunogen is recombinant human E2F-3 protein.

Target Information

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.