Thermo Fisher Scientific FAM65A Polyclonal Antibody
Rabbit polyclonal antibody against human FAM65A protein. Validated for Western blot and immunoprecipitation. Supports studies on cell polarity and migration. Supplied as unconjugated liquid, 1 mg/mL concentration, stored at 4°C.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1173 and 1223 of human Family with Sequence Similarity 65, Member A (FAM65A) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
FAM65A is a downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). It acts as an adapter protein linking active Rho proteins to STK24 and STK26 kinases, positively regulating Golgi reorientation in polarized cell migration upon Rho activation. It is also involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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