Thermo Fisher Scientific TRF2 Polyclonal Antibody
TRF2 단백질을 검출하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다. PBS와 50% 글리세롤 용액에 보관되며, -20°C에서 안정적으로 저장 가능합니다.
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Applications
Tested Applications and Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TERF2 (Accession Q15554), corresponding to amino acid residues G339–G389. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900703 |
Product Specific Information
Antibody detects endogenous levels of total TRF2.
Target Information
TRF2 is a ubiquitously expressed protein implicated in the control of telomere length. Like TRF1, TRF2 contains a Myb-related DNA binding motif and binds to duplex TTAGGG repeats, localizing to all human telomeres in metaphase chromosomes. It is thought to protect chromosome ends by maintaining correct telomere structure. Mutant forms of TRF2 have been linked to the prevention of senescence in primary human cells, and inhibition of TRF2 has been shown to induce apoptosis in certain mammalian cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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