Thermo Fisher Scientific UCP4 Polyclonal Antibody
UCP4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 고순도의 affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정합니다.
- 카탈로그번호
- PA5100668
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC25A27 (Accession O95847), corresponding to amino acid residues L245–P295 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850172 |
Product Specific Information
This antibody detects endogenous levels of total SLC25A27.
Target Information
UCP4 (Uncoupling Protein 4) is a 323 amino acid mitochondrial protein belonging to the large mitochondrial substrate carrier family with three Solcar repeats.
It functions as a mitochondrial transport carrier facilitating the transfer of anions from the inner to the outer mitochondrial membrane and the return of protons in the opposite direction.
UCP4 reduces the mitochondrial membrane potential and is involved in thermoregulatory heat production by creating proton leaks across the inner mitochondrial membrane, uncoupling oxidative phosphorylation from ATP synthesis.
It is primarily expressed in adult and fetal brain, with lower levels in spinal cord, corpus callosum, and substantia nigra.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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