Thermo Fisher Scientific IL-15RA Polyclonal Antibody
IL-15RA 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, ELISA 등에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로 T 및 NK 세포 활성화 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human IL-15RA (amino acids 51–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 15 receptor alpha (IL-15RA) is a cytokine receptor that binds IL-15 with high affinity. IL-15 regulates T and natural killer (NK) cell activation and proliferation. IL-15 and IL-2 receptors share two subunits (IL-2Rβ and IL-2Rγ), and IL-15RA is structurally related to IL-2RA, an IL-2-specific alpha subunit required for high-affinity IL-2 binding. Unlike IL-2RA, IL-15RA binds IL-15 with high affinity independently of other subunits. IL-15RA is associated with enhanced cell proliferation and increased expression of apoptosis inhibitors Bcl-xL and Bcl-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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