Thermo Fisher Scientific TNFRSF11B Recombinant Rabbit Monoclonal Antibody (340)
Human TNFRSF11B(Osteoprotegerin)을 인식하는 recombinant rabbit monoclonal antibody. 높은 특이성과 재현성을 제공하며, ELISA에 최적화됨. 보존제 무첨가로 순도 높음. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 340 |
| Immunogen | Recombinant Human Osteoprotegerin/TNFRSF11B protein (Met1–Leu401) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786616 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity to diverse targets due to the large rabbit immune repertoire
This antibody is specific for Human Osteoprotegerin/TNFRSF11B.
Target Information
The TNFRSF11B gene encodes a member of the TNF-receptor superfamily. This osteoblast-secreted decoy receptor acts as a negative regulator of bone resorption by binding to its ligand, osteoprotegerin ligand, which are key regulators of osteoclast development.
Studies in mice suggest roles in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants have been reported, though their full-length nature remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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