Thermo Fisher Scientific TLX2 Polyclonal Antibody
TLX2 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. 인간 TLX2에 반응하며 IHC(P) 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성 제공. 연구용으로만 사용.
- 카탈로그번호
- PA559372
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TLX2. Recombinant protein control fragment (Product #RP-98392). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648505 |
Product Specific Information
Immunogen sequence:
GIDQILSGPE TPGGGLGLGR GGQGHGENGA FSGGYHGASG YGPAGSL
Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 74%
Target Information
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor crucial for the development of the peripheral nervous system. TLX2 is regulated by PHOX2A and PHOX2B during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may contribute to tumorigenesis of gastrointestinal stromal tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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