Thermo Fisher Scientific LTA Monoclonal Antibody (2D8)
인간 LTA(TNF beta)를 인식하는 마우스 단클론 항체로, Western blot과 ELISA에 사용 가능. 비결합형 액상 형태이며, PBS(pH 7.4) 버퍼에 보존제 없이 제공. -20°C에서 보관하며, 친화 크로마토그래피로 정제됨.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D8 |
| Immunogen | Recombinant Flag/His fusion protein corresponding to amino acids 58–205 of human LTA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
HSTLKPAAHL IGDPSKQNSL LWRANTDRAF LQDGFSLSNN SLLVPTSGIY FVYSQVVFSG KAYSPKATSS PLYLAHEVQL FSSQYPFHVP LLSSQKMVYP GLQEPWLHSM YHGAAFQLTQ GDQLSTHTDG IPHLVLSPST VFFGAFAL
Target Information
TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface.
This protein mediates various inflammatory, immunostimulatory, and antiviral responses, contributes to secondary lymphoid organ formation, and plays a role in apoptosis.
Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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