Thermo Fisher Scientific COX6A2 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended positive control: Raji
• Predicted reactivity: Rhesus Monkey (100%)
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex.
This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, which is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa, encoded by a different gene, is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.