Thermo Fisher Scientific PDGFRA Monoclonal Antibody (OTI2E9), TrueMAB
PDGFRA 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western blot 및 IHC(P)에서 사용 가능. 인간 유래 항원(aa 32-324)을 기반으로 제작되었으며, 액상 형태로 1 mg/mL 농도. PBS, BSA, 글리세롤 완충액에 보관하며 -20°C에서 안정적 저장 가능.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–324 of human PDGFRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PDGFRA (Platelet-Derived Growth Factor Receptor Alpha) is a cell surface receptor tyrosine kinase that binds members of the platelet-derived growth factor family. These growth factors act as mitogens for cells of mesenchymal origin. The receptor can form homodimers or heterodimers with PDGFRB, influencing various developmental processes. Studies in knockout mice indicate PDGFRA’s crucial role in kidney development, as heterozygous mutants exhibit defective renal phenotypes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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