Thermo Fisher Scientific NKIRAS1 Monoclonal Antibody (OTI6C11), TrueMAB
Human NKIRAS1 단백질을 인식하는 mouse monoclonal antibody. Western blot, IHC, ICC/IF에 적합. 고순도 affinity chromatography 정제. PBS/BSA/glycerol buffer에 보관, -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C11 |
| Immunogen | Full length human recombinant protein of human NKIRAS1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are small proteins similar to Ras-like small GTPases that associate with Ikappa-B, an inhibitor of the transcription factor NF-kappa-B.
Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta, with Ikappa-B-beta containing a unique 47-amino acid region within its ankyrin domain.
Inactive Ikappa-B-alpha–NF-kappa-B complexes can shuttle in and out of the nucleus, while Ikappa-B-beta–NF-kappa-B complexes are retained in the cytoplasm.
KappaB-ras proteins preferentially bind to the Ikappa-B-beta form through this unique insert, modulating its cellular location and regulating its degradation rate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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