Thermo Fisher Scientific POM121 Polyclonal Antibody
Human POM121 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 핵공복합체(NPC) 연구에 활용됩니다.
- 카탈로그번호
- PA583979
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human POM121 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791131 |
Product Specific Information
Immunogen sequence:
MVCSPVTLRI APPDRRFSRS AIPEQIISST LSSPSSNAPD PCAKETVLSA LKEKKKK
Target Information
POM121 (POM121 membrane glycoprotein), also known as POM121A (nuclear envelope pore membrane protein POM121A), NUP121 (nucleoporin Nup121) or pore membrane protein of 121 kDa, is a 1,249 amino acid single-pass membrane protein that exists as three alternatively spliced isoforms and belongs to the POM121 family.
Encoded by a gene that maps to human chromosome 7q11.23, POM121 is highly conserved and localizes to the nucleus membrane and endoplasmic reticulum membrane.
An essential component of the nuclear pore complex (NPC), POM121 is mandatory for nuclear envelope formation and may play a role in biogenesis of the NPC.
POM121 associates with the central spoke ring complex and is involved in anchoring components of the pore complex to the pore membrane via its F-X-F-G repeat-containing domain.
Overexpression of POM121 induces the formation of cytoplasmic annulate lamellae (AL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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