Thermo Fisher Scientific ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) Monoclonal Antibody (SPM501)
ACTH 단백질을 인식하는 SPM501 클론의 mouse monoclonal 항체. Paraffin, PFA 고정 조직 및 세포에서 IHC, ICC, Flow cytometry, ELISA에 사용 가능. Protein A/G 정제, 1 mg/mL 농도의 액상 형태. 인간 시료 반응성, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM501 |
| Immunogen | Synthetic peptide corresponding to aa25–39 of human ACTH (NGAEDESAEAFPLEF) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
ACTH (adrenocorticotropic hormone) is a hormone that plays a key role in stimulating the adrenal cortex. It is generated by cleavage of the proopiomelanocortin (POMC) precursor, which also produces other peptides such as MSH and beta endorphin. ACTH is secreted from the anterior pituitary in response to corticotropin-releasing hormone from the hypothalamus. It promotes secretion of glucocorticoids like cortisol, but has limited effect on mineralocorticoids such as aldosterone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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