Thermo Fisher Scientific INT11 Polyclonal Antibody
Rabbit 유래 다클론 항체로, INT11 단백질을 표적하며 WB, IHC, IP 등 다양한 응용 가능. 액상 형태로 제공되며 4°C 보관. FFPE 조직에서 citrate buffer(pH 6.0) 전처리 권장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 550 and 600 of human integrator complex subunit 11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits: p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is essential for chromatin assembly after replication. It is differentially phosphorylated in a cell cycle-dependent manner and typically localized in the nucleus except during mitosis, when it relocates to the cytoplasm. This protein belongs to the WD-repeat HIR1 family and may also play a role in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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