Thermo Fisher Scientific NPR3 Monoclonal Antibody (OTI11A6), TrueMAB
인간 NPR3 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. 동결건조 형태로 제공되며, 1 mg/mL 농도로 재구성 가능. 혈압 및 체액 조절 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11A6 |
| Immunogen | Full-length human recombinant NPR3 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The NPR3 gene encodes one of three natriuretic peptide receptors. These receptors regulate blood volume, pressure, pulmonary hypertension, cardiac function, and certain metabolic and growth processes.
NPR3 functions as a clearance receptor that removes circulating and extracellular natriuretic peptides through receptor-mediated endocytosis. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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