Thermo Fisher Scientific Actin-like 7B Polyclonal Antibody
Human Actin-like 7B 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 고순도 항원 친화 크로마토그래피 정제, 0.2 mg/mL 농도, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Actin-like 7B. Recombinant protein control fragment (Product #RP-93001). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637638 |
Product Specific Information
Immunogen sequence:
MATRNSPMPL GTAQGDPGEA GTRPGPDASL RDTGAATQLK MKPRKVHKIK AVIIDLGSQY CKCGYAGEPR PTYFISSTVG KRCPEAADAG DTRKWTL
Antigen sequence identity:
- Mouse: 74%
- Rat: 76%
Target Information
The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold (ATP-binding cleft) as a common feature.
The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration, and chromatin remodeling.
This gene and ACTL7A are intronless and located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31.
Mutational analysis of ACTL7B suggests it is unlikely to be involved in dysautonomia. ACTL7B is predominantly expressed in the testis, and its exact function remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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