Thermo Fisher Scientific ID3 Monoclonal Antibody (OTI4D1), Biotin, TrueMAB
Human ID3 단백질을 인식하는 마우스 단클론 항체로, Biotin 결합 형태입니다. ELISA 및 Luminex 분석에 사용 가능하며, 고순도의 Affinity chromatography 정제 방식으로 제조되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| ELISA (ELISA) | 1:250–1:1,000 | |
| Luminex (LUM) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D1 |
| Immunogen | Full length human recombinant protein of human ID3 produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Members of the Id family of basic helix-loop-helix (bHLH) proteins include ID1, ID2, ID3, and ID4. These proteins are ubiquitously expressed and dimerize with class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA, thus negatively regulating DNA binding of bHLH proteins.
ID proteins function to inhibit muscle-specific gene expression by preventing DNA binding of E12 and Myo D. During muscle cell differentiation, reduced ID protein levels allow E12 and/or E47 to interact with Myo D and myogenin, activating myogenic differentiation. Expression of ID proteins is strongly dependent on growth factor activation, and reduction of ID mRNA delays reentry into the cell cycle after growth factor stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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