Thermo Fisher Scientific RBM15 Polyclonal Antibody
Thermo Fisher Scientific RBM15 Polyclonal Antibody는 인간 및 마우스 시료에 반응하며, WB, IHC, ELISA에 사용 가능합니다. 재조합 단백질을 면역원으로 사용한 Rabbit IgG 폴리클로날 항체로, 높은 특이성과 안정성을 제공합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 530–780 of human RBM15 (NP_001188474.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806439 |
Product Specific Information
Immunogen sequence:
EHRYQQQYLQ PLPLTHYELV TDAFGHRAPD PLRGARDRTP PLLYRDRDRD LYPDSDWVPP PPPVRERSTR TAATSVPAYE PLDSLDRRRD GWSLDRDRGD RDLPSSRDQP RKRRLPEESG GRHLDRSPES DRPRKRHCAP SPDRSPELSS SRDRYNSDND RSSRLLLERP SPIRDRRGSL EKSQGDKRDR KNSASAERDR KHRTTAPTEG KSPLKKEDRS DGSAPSTSTA SSKLKSPSQK QDGGTAPVAS A
Positive Samples: HL-60, HepG2, 293T, Jurkat, Mouse thymus, Mouse spleen
Cellular Location: Nucleus, Nuclear membrane, Nuclear speckle, Peripheral membrane protein, Nucleoplasm
Target Information
RBM15 may function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs present in many retrotransposons. It binds pre-mRNA with high affinity, potentially targeting mRNP to export helicase DBP5 independently of splicing-mediated NXF1 deposition, enabling export prior to splicing. It may also be involved in HOX gene regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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