Thermo Fisher Scientific CRYBB1 Polyclonal Antibody
Human CRYBB1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500–1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CRYBB1. Recombinant protein control fragment (Product # RP-108304) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789254 |
Product Specific Information
Immunogen sequence:
TTVPITSAKA AELPPGNYRL VVFELENFQG RRAEFSGECS NLADRGFDRV RSIIVSAGPW VAFEQSNFRG EMFILEKGEY PRWNTWSSSY RSDRLMSFRP IKMDAQE
Target Information
Crystallins are separated into two classes: taxon-specific (enzyme) and ubiquitous. The latter are major proteins of the vertebrate eye lens, maintaining transparency and refractive index. Lens fiber cells lose nuclei during development, retaining crystallins throughout life, making them highly stable.
Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins form a superfamily. Alpha and beta families are subdivided into acidic and basic groups. Beta-crystallins, the most heterogeneous, vary by the presence of a C-terminal extension (present in the basic group). They can form dimers or heterodimers with other beta-crystallins.
The CRYBB1 gene, a beta basic group member, undergoes extensive N-terminal cleavage during lens maturation and is part of a cluster with beta-A4, beta-B2, and beta-B3 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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