Thermo Fisher Scientific RAB43 Polyclonal Antibody
RAB43 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human RAB43 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690615 |
Target Information
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that recruits downstream effectors responsible for vesicle formation, movement, tethering, and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. It is involved in retrograde transport from the endocytic pathway to the Golgi apparatus and in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. RAB43 is required for the structural integrity of the Golgi complex and plays a role in the maturation of phagosomes that engulf pathogens such as S. aureus and M. tuberculosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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