Thermo Fisher Scientific GTF3A Monoclonal Antibody (3F7)
인간 GTF3A 단백질을 표적으로 하는 마우스 단일클론 항체로 ELISA에 적합합니다. GST 태그가 포함된 재조합 단백질을 면역원으로 사용했습니다. 액상 형태이며 PBS 버퍼에 보존제가 없습니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F7 |
| Immunogen | GTF3A (NP_002088, 185–274 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
NQQKQYICSF EDCKKTFKKH QQLKIHQCQN TNEPLFKCTQ EGCGKHFASP SKLKRHAKAH EGYVCQKGCS FVAKTWTELL KHVRETHKEE
Target Information
The product of this gene is a zinc finger protein with nine Cys[2]-His[2] zinc finger domains.
It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes.
The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex.
This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex.
The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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