Thermo Fisher Scientific BAD Polyclonal Antibody
BAD 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BAD. Recombinant protein control fragment (Product #RP-95086). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790159 |
Product Specific Information
Immunogen sequence:
QEDSSSAERG LGPSPAGDGP SGSGKHHRQA PGLLWDASHQ QEQPTSSSHH GGAGAVEIRS RHSSYPAGTE DDEGMG
Target Information
The protein encoded by BAD is a member of the BCL-2 family, known as regulators of programmed cell death. BAD promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity. Its proapoptotic activity is regulated through phosphorylation by kinases such as AKT and MAP kinase, and by phosphatase calcineurin. Alternative splicing of this gene results in two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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