Thermo Fisher Scientific OBFC2B Polyclonal Antibody
Thermo Fisher Scientific의 OBFC2B Polyclonal Antibody는 인간 및 마우스 반응성을 가진 Rabbit IgG 항체로, 단백질 A 및 항원 친화 크로마토그래피로 정제됨. SOSS 복합체 구성요소로 DNA 손상 복구 연구에 적합하며, Western blot에 1:1,000 희석으로 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 183–211 amino acids from the C-terminal region of human OBFC2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633699 |
Product Specific Information
Predicted to react with bovine and rat based on sequence homology.
Target Information
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.
In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, particularly to polypyrimidines.
The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response, including cell-cycle checkpoint activation, recombinational repair, and maintenance of genomic stability.
Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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