Thermo Fisher Scientific NRF1 Polyclonal Antibody
NRF1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot과 IHC에 사용 가능. Human 시료에 반응하며, Protein A로 정제된 1 mg/mL 농도의 액상 항체. 세포 성장 및 미토콘드리아 유전자 발현 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.25 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human NRF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607684 |
Product Specific Information
Peptide sequence:
IVLSGETAAA VGALTGVQDA NGLFMADRAG RKWILTDKAT GLVQIPVSMY
Sequence homology:
- Human: 100%
- Rat: 91%
Target Information
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
The protein is also associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants encoding the same protein have been characterized. Additional variants encoding different protein isoforms have been described but not fully characterized.
Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 (official symbol: NFE2L1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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