Thermo Fisher Scientific mGluR2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1127)
Thermo Fisher Scientific의 mGluR2 VHH-8His-Cys-tag 단클론 항체(SAA1127)는 CHO 세포에서 발현된 Alpaca 유래 재조합 항체입니다. ELISA에 적합하며, 인간 mGluR2 단백질을 인식합니다. 금속 킬레이트 크로마토그래피로 정제되었으며, 1 mg/mL 농도로 PBS에 보존됩니다.
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Thermo Fisher Scientific mGluR2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1127)
Applications
- ELISA (Assay-dependent)
- Compatible with Direct ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1127 |
| Immunogen | Recombinant Human GRM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. For many years, it was considered to act only on ligand-gated receptor channels—NMDA, AMPA, and kainate receptors—responsible for fast excitatory synaptic transmission.
Recently, glutamate has been shown to regulate enzymes producing second messengers via specific G-protein-coupled receptors, termed metabotropic glutamate receptors (mGluRs).
Group I receptors stimulate phospholipase C, increasing phosphoinositide turnover and calcium release. Group II and III receptors inhibit adenylyl cyclase.
Group I includes mGluR1a and mGluR5, while Group II includes mGluR2 and mGluR3.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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