Thermo Fisher Scientific PLCE1 Polyclonal Antibody
PLCE1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인체 및 설치류 등 다양한 종에 반응하며, 고순도 Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며, 연구용으로 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PLCE1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PLCE1 (Accession Q9P212), corresponding to amino acid residues R2267–Q2302 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850354 |
Product Specific Information
Antibody detects endogenous levels of total PLCE1.
Target Information
The PLCE1 gene encodes a phospholipase enzyme that hydrolyzes phosphatidylinositol-4,5-bisphosphate to produce second messengers inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These messengers regulate cellular processes such as growth, differentiation, and gene expression. The enzyme is regulated by Ras and Rho family GTPases and heterotrimeric G proteins. It also possesses guanine nucleotide exchange (GEF) activity. Mutations in PLCE1 cause early-onset nephrotic syndrome, characterized by proteinuria, edema, and glomerulosclerosis. Alternative splicing produces multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.