Thermo Fisher Scientific Aquaporin 4 Polyclonal Antibody
Aquaporin 4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용에 사용 가능. 인간, 마우스, 돼지, 랫트 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:20 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse AQP4, amino acids 271–323 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In skeletal muscle, AQP4 (aquaporin 4, also known as mercurial insensitive water channel) localizes to the sarcolemma of fast-twitch muscle fibers.
Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved across animals, plants, and bacteria.
Many isoforms of aquaporin have been identified in mammals (AQP0–AQP10). Aquaporins are widely distributed, and multiple types can be present in the same cell.
While most aquaporins are only permeable to water, AQP3, AQP7, AQP9, and one of the two AQP10 transcripts are also permeable to urea and glycerol.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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