Thermo Fisher Scientific SARS-CoV Spike Protein RBD Recombinant Rabbit Monoclonal Antibody (0E9W9)

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:5,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
ADYSVLYNST FFSTFKCYGV SATKLNDLCF SNVYADSFVV KGDDVRQIAP GQTGVIADYN YKLPDDFMGC VLAWNTRNID ATSTGNYNYK YRYLRHGKLR P

Target Information

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus causing illnesses ranging from mild cold-like symptoms to severe respiratory distress and death. The Spike (S) protein plays a crucial role in viral attachment, fusion, and entry, serving as a major target for antibodies, entry inhibitors, and vaccines.

The receptor-binding domain (RBD) of the Spike protein binds strongly to human and bat ACE2 receptors. Notably, the SARS-CoV-2 RBD has a higher binding affinity to ACE2 than the SARS-CoV RBD. The S1 subunit contains the RBD that specifically interacts with ACE2 receptors on target cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.