Thermo Fisher Scientific DOPA Decarboxylase Monoclonal Antibody (CL2962)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL2962

Immunogen

Recombinant protein corresponding to Human DDC if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DOPA Decarboxylase,uniProtId:P20711-1,ncbiNodeId:9606,antigenRange:114-221,antigenLength:480,antigenImageFileName:MA5-31379_DOPA_Decarboxylase_P20711-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31379_DOPA_Decarboxylase_P20711-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2787016

Product Specific Information

Immunogen sequence: LETVMMDWLG KMLELPKAFL NEKAGEGGGV IQGSASEATL VALLAARTKV IHRLQAASPE LTQAAIMEKL VAYSSDQAHS SVERAGLIGG VKLKAIPSDG NFAMRASA

Target Information

DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson`s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.