Thermo Fisher Scientific HACE1 Monoclonal Antibody (OTI4F10), TrueMAB
HACE1 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 적합. HEK293T 세포에서 발현된 full-length human HACE1 항원을 면역원으로 사용. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 연구용 전용 제품.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F10 |
| Immunogen | Full length human recombinant protein of human HACE1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases.
Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion.
Acts by mediating ubiquitination during mitotic Golgi disassembly, which serves as a signal for Golgi reassembly later, after cell division.
Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens.
May also act as a transcription regulator via its interaction with RARB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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