Thermo Fisher Scientific RGS17 Polyclonal Antibody
RGS17 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. 인간 및 생쥐에 반응하며, 액상 형태로 제공. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 보장.
- 카탈로그번호
- PA5104091
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RGS17 (Accession Q9UGC6), corresponding to amino acid residues M1–V43 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853419 |
Product Specific Information
Antibody detects endogenous levels of total RGS17.
Target Information
This gene encodes a member of the regulator of G-protein signaling family. The protein contains a conserved 120 amino acid RGS domain and a cysteine-rich region. It attenuates G-protein signaling by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), accelerating GTP hydrolysis to GDP. This process enables G alpha subunits to reassociate with G beta/gamma heterodimers, forming inactive G-protein heterotrimers and terminating the signal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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