Thermo Fisher Scientific Bcl-xL Polyclonal Antibody
Thermo Fisher Scientific의 Bcl-xL Polyclonal Antibody는 인간 BCL2-like 1 단백질(1–50번 잔기)을 면역원으로 한 Rabbit IgG 항체입니다. Western blot에 최적화되어 있으며, 인간, 마우스, 랫, 피그에서 반응이 예측됩니다. 액상 형태로 1 mg/mL 농도, 항원 친화 크로마토그래피로 정제되었습니다.
- 카탈로그번호
- A300284A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:10,000–1:25,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1–50 of human BCL2-like 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, and Pig
Target Information
BCL-XL is a member of the BCL-2 protein family, which forms hetero- or homodimers and acts as anti- or pro-apoptotic regulators involved in diverse cellular activities.
Located at the outer mitochondrial membrane, BCL-XL regulates VDAC opening, controlling mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release—key factors in apoptosis induction.
Two alternatively spliced transcript variants encode distinct isoforms: the longer isoform inhibits apoptosis, while the shorter form promotes it.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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