Thermo Fisher Scientific NAT11 Polyclonal Antibody
Human NAT11 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 ICC/IF에 적합합니다. 재조합 단백질을 면역원으로 사용했으며, 고순도 항원 친화 크로마토그래피 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific NAT11 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NAT11. Recombinant protein control fragment (Product #RP-97302). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644481 |
Product Specific Information
Immunogen sequence:
DLTKTNMQTM YEQSEWGWKD REKREEMTDD RAWYLIAWEN SSVPVAFSHF RFDVECGDEV LYCYEVQLES KV
Antigen sequence identity:
- Mouse: 99%
- Rat: 97%
Target Information
N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring on approximately 57% and 84% of yeast and human proteins respectively. There are several N-terminal acetylating enzyme complexes (NatA–NatE). Unlike other complexes, NatD is composed of a single protein, NAT11, which acetylates the Serine N-termini of histones H2A and H4 in yeast. The functional role of these modifications remains unclear; yeast lacking NAT11 show normal growth and no observable phenotypes. The role of the human homolog is likewise unknown.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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