Thermo Fisher Scientific NAT11 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NAT11. Recombinant protein control fragment (Product #RP-97302). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NAA40,uniProtId:Q86UY6-1,ncbiNodeId:9606,antigenRange:75-146,antigenLength:237,antigenImageFileName:PA5-58121_NAA40_Q86UY6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58121_NAA40_Q86UY6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644481

Product Specific Information

Immunogen sequence: DLTKTNMQTM YEQSEWGWKD REKREEMTDD RAWYLIAWEN SSVPVAFSHF RFDVECGDEV LYCYEVQLES KV

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 97%.

Target Information

N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring on approximately 57% and 84% on yeast and human proteins respectively. There are several N-terminal acetylating enzyme complexes (NatA - NatE). Unlike the other complexes, NatD is composed of a single protein, NAT11, and has recently been described to acetylate the Serine N-termini of histones H2A and H4 in yeast. The role these modifications play is unknown; yeast that do not express NAT11 grow at normal rates and have no observable phenotypes. The role of the human homolog is likewise unknown.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.