
Thermo Fisher Scientific POMGNT1 Polyclonal Antibody
Thermo Fisher Scientific의 POMGNT1 Polyclonal Antibody는 Mouse에 반응하며 Rabbit에서 생산된 IgG 형 항체입니다. Western blot에 적합하며, POMGNT1 단백질 연구에 사용됩니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse POMGNT1 (aa 47–96) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2690144 |
Product Specific Information
This target displays homology in the following species:
Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 86%; Rat: 100%
Target Information
The product of the POMGNT1 gene, protein O-mannose beta-1,2-N-acetylglucosaminyltransferase, participates in O-mannosyl glycan synthesis.
POMGnT1 is an N(in)/C(out) (type II) membrane protein localized in the medial-Golgi that initiates the conversion of high mannose N-glycans to complex N-glycans.
Specifically, POMGnT1 is a glycosylation enzyme that participates in the synthesis of O-mannosyl glycan, a laminin-binding ligand of alpha-dystroglycan that is rarely synthesized in mammals.
Mutations in the POMGNT1 gene cause muscle-eye-brain disease (MEB), an autosomal recessive disorder characterized by congenital muscular dystrophy, ocular abnormalities, and lissencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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