Thermo Fisher Scientific TLR8 Monoclonal Antibody (OTI3A6), TrueMAB
TLR8 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 사용 가능. Human 시료에 반응하며, Lyophilized 형태로 제공. 재구성 후 약 1 mg/mL 농도로 사용. 선천면역 연구용으로 적합.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–153 of human TLR8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The TLR8 protein is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity.
TLRs are highly conserved from Drosophila to humans and recognize pathogen-associated molecular patterns (PAMPs) expressed on infectious agents, mediating cytokine production for effective immune responses.
The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes and is located near TLR7 on the X chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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