Thermo Fisher Scientific CTDSP1 Polyclonal Antibody
CTDSP1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot 및 IHC(P)에서 사용 가능하며, 인간과 생쥐에 반응. 액상 형태로 제공되며 0.5 mg/mL 농도, TBS 버퍼에 보존. 연구용으로만 사용 가능.
- 카탈로그번호
- PA537961
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence EAKAQDSDKIC, from the internal region of CTDSP1 (aa 82–92) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554565 |
Product Specific Information
- Predicted to react with rat, dog, and cow based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
CTDSP1 is a class 2C phosphatase with activity dependent on the conserved DxD motif. Expression of CTDSP1 inhibits activated transcription from several promoter-reporter gene constructs, while a mutant lacking phosphatase activity enhances transcription.
REST/NRSF complex recruits SCPs to neuronal genes containing RE1 elements, leading to neuronal gene silencing in non-neuronal cells. Phosphatase-inactive SCP forms interfere with REST/NRSF function and promote neuronal differentiation. SCP activity is an evolutionarily conserved transcriptional regulator that globally silences neuronal genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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