Thermo Fisher Scientific MIER1 Polyclonal Antibody
Rabbit polyclonal antibody against human MIER1. Validated for ICC/IF applications. Antigen affinity purified and supplied as a liquid at 0.1 mg/mL. Suitable for research use only, not for diagnostic or resale purposes.
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Applications and Tested Dilution
- Application: Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MIER1. Recombinant protein control fragment (Product #RP-106272) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664017 |
Product Specific Information
Immunogen sequence:
GPTGGNKKPLH ADMDTNGYET DNLTTDPKLA HMTARNENDF DEKSERPAKR RRVNSNGKES PGSSEFFQEA VSHGKFEELE NTDD
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 87%
Target Information
The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins, which may have important implications for transcriptional regulation. Repressor activity is mediated through interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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