Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI2F7), TrueMAB
ABCB1 단백질을 인식하는 마우스 단클론 항체로, Western blot에 적합. 인간 시료 반응성, TrueMAB 포맷. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능. 다약제 내성 관련 연구에 활용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 995–1280 of human ABCB1 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The membrane-associated protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein is part of the MDR/TAP subfamily, involved in multidrug resistance. It acts as an ATP-dependent drug efflux pump with broad substrate specificity, reducing drug accumulation in multidrug-resistant cells and contributing to anticancer drug resistance. It also functions as a transporter in the blood-brain barrier.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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