Thermo Fisher Scientific ERAL1 Polyclonal Antibody
Human ERAL1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약이며, 0.1 mg/mL 농도. 미토콘드리아 리보솜 조립 관련 연구용에 적합.
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- PA555073
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ERAL1 (aa 231–322). Recombinant protein control fragment (Product #RP-93314). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641085 |
Product Specific Information
Immunogen sequence:
SVLVMNKVDC LKQKSVLLEL TAALTEGVVN GKKLKMRQAF HSHPGTHCPS PAVKDPNTQS VGNPQRIGWP HFKEIFMLSA LSQEDVKTLK QY
Highest antigen sequence identity to orthologs:
- Mouse: 74%
- Rat: 73%
Target Information
ERAL1 encodes a mitochondrial GTPase that binds to the 3′ terminal stem loop of 12S mitochondrial rRNA and is essential for assembly of the 28S small mitochondrial ribosomal subunit. Deletion of ERAL1 causes mitochondrial dysfunction, growth retardation, and apoptosis. Multiple transcript variants encoding different isoforms exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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