Thermo Fisher Scientific LRRK1 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): Tested dilution 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MSQRPPSMYW CVGPEESAVC PERAMETLNG AGDTGGKPST RGGDPAARSR RTEGIRAAYR RGDRGGARDL LEEACDQCAS QLEKGQLLSI PAAYGDLEMV RYLLSKRLVE LPTEPTDDNP AVVAAYFGHT AVVQELLESL PGPCSPQRLL NWMLALACQR GHLGVVKLLV LTHGADPESY AVRKNEFPVI VRLPLYAAIK SGNEDIAIFL LRHGAYFCSY ILLDSPDPSK HLLRKYFIEA SPLPSSYPGK TVSSHCLWSV F

Target Information

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate signal transduction in eukaryotic cells, regulating:

• Cellular metabolism
• Transcription
• Cell cycle progression
• Cytoskeletal rearrangement and movement
• Apoptosis and differentiation

With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes. It is classified into 8 major groups based on sequence comparison of tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.