Thermo Fisher Scientific Arfaptin 2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 57-121. Recombinant protein control fragment (Product #RP-109780). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Arfaptin 2,uniProtId:P53365-1,ncbiNodeId:9606,antigenRange:57-121,antigenLength:341,antigenImageFileName:PA5-144775_Arfaptin_2_P53365-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144775_Arfaptin_2_P53365-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3091826

Product Specific Information

Immunogen sequence: GSGDGLIPTG SGRHPSHSTT PSGPGDEVAR GIAGEKFDIV KKWGINTYKC TKQLLSERFG RGSRT

Antigen sequence identity: Mouse 98%; Rat 98%

Target Information

Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660). Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site (PubMed:31204568). In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.