Thermo Fisher Scientific MYADM Polyclonal Antibody
Rabbit polyclonal antibody against human MYADM protein. Validated for IHC, ICC/IF, and ELISA. Recognizes recombinant MYADM (1–40 AA). Suitable for research on hematopoietic differentiation and leukemia. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Reference |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:20–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | – |
| ELISA | Assay-dependent | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Myeloid-associated differentiation marker protein (1–40 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.02 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | –20°C or –80°C (preferred) |
| Shipping Conditions | Wet ice |
| RRID | AB_3091492 |
Target Information
MYADM, part of the MAL family, is a 322-amino acid protein containing seven hydrophobic transmembrane domains and multiple phosphorylation consensus sites. It shows sequence homology with the T-cell differentiation protein MAL and plasmolipin, sharing 75.8% identity with the mouse in transmembrane regions. MYADM is associated with hematopoietic cell differentiation and acute promyelocytic leukemia. Its expression increases in NB4 cells treated with all-trans retinoic acid, while downregulation inhibits bone marrow colony formation. MYADM may serve as a marker for hematopoietic differentiation and as a target for diagnostic, prognostic, or therapeutic research. It is expressed in brain and pancreatic islet cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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