Thermo Fisher Scientific BRMS1 Polyclonal Antibody
BRMS1 단백질을 인식하는 Thermo Fisher Scientific의 다클론성 항체로, Western blot, IHC, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트에 반응하며, 고순도 친화 크로마토그래피 정제. 액상 형태로 -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 90–210 of human BRMS1 (NP_056214.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.91 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913884 |
Product Specific Information
- Positive test controls: Mouse kidney, Mouse testis
- Localization: Cytoplasm, Nucleus
- Immunogen sequence:
LEEVGAERAP EYTEPLGGLQ RSLKIRIQVA GIYKGFCLDV IRNKYECELQ GAKQHLESEK LLLYDTLQGE LQERIQRLEE DRQSLDLSSE WWDDKLHARG SSRSWDSLPP SKRKKAPLVS G
Target Information
This gene reduces the metastatic potential, but not the tumorigenicity, of human breast cancer and melanoma cell lines.
The encoded protein localizes primarily to the nucleus and is part of the mSin3a histone deacetylase complex (HDAC).
It contains two coiled-coil motifs and several imperfect leucine zipper motifs.
Alternative splicing produces two transcript variants encoding different isoforms.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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