Thermo Fisher Scientific UACA Polyclonal Antibody
Thermo Fisher Scientific의 UACA Polyclonal Antibody는 인간 UACA 단백질을 인식하는 토끼 유래 IgG 항체로, WB, IHC, IP 등 다양한 응용에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 1 mg/mL 농도입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human uveal autoantigen with coiled-coil domains and ankyrin repeats |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways: apoptosome up-regulation, LGALS3/galectin-3 down-regulation, and NF-kappa-B inactivation. Regulates redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates LGALS3 expression by inhibiting NFKB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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