Thermo Fisher Scientific Human HTRA2 Synthetic Peptide
Human HTRA2 단백질의 C-말단 15개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-20064의 블로킹 펩타이드로 사용 가능. 인간 단백질 연구용으로 적합하며, 고순도 정제 및 PBS 버퍼에 보관. 연구용 전용 제품.
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Thermo Fisher Scientific Human HTRA2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human OMI.
PEP-0183 can be used as a blocking peptide with polyclonal antibody PA5-20064.
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein, called Omi/HtrA2, is a mitochondrial protein that binds to IAP. Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis, indicating that Omi could participate in the mitochondrial apoptotic pathway.
주의사항
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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