Thermo Fisher Scientific US12 Polyclonal Antibody
Thermo Fisher Scientific US12 Polyclonal Antibody는 Human herpesvirus 1 ICP47 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot 및 ELISA에 사용 가능하며, 단백질 G로 정제된 액상 형태입니다. 면역 반응 억제 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human herpesvirus 1 ICP47 protein (US12) (1–88aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.249 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3091700 |
Target Information
Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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