Thermo Fisher Scientific PSMB7 Monoclonal Antibody (OTI1E1), TrueMAB
PSMB7 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P) 분석에 적합. Human 및 Mouse 시료에 반응하며, Affinity chromatography로 정제된 고순도 항체. -20°C에서 보관, 연구용 전용.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PSMB7 Monoclonal Antibody (OTI1E1), TrueMAB
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 58–277 of human PSMB7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of 4 rings of 28 non-identical subunits. Two rings consist of 7 alpha subunits and two rings of 7 beta subunits. Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome processes class I MHC peptides. The PSMB7 gene encodes a proteasome B-type family member (T1B family), a 20S core beta subunit. Expression is downregulated by gamma interferon, and proteolytic processing is required for maturation. This subunit is replaced by catalytic subunit 2i (proteasome beta 10 subunit) in the immunoproteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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