Thermo Fisher Scientific Calpain 13 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: A549, HeLa
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

The calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that are nonlysosomal intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific forms. The ubiquitous enzymes are heterodimers composed of distinct large catalytic subunits and a common small regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme Calpain 1. Several transcript variants encoding two different isoforms have been identified. Diseases associated with CAPN1 include Spastic Paraplegia 76 (Autosomal Recessive) and Spasticity.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.