Thermo Fisher Scientific DTYMK Monoclonal Antibody (OTI1C4), TrueMAB
DTYMK 단백질을 인식하는 Mouse Monoclonal Antibody로, Western blot, ICC/IF, Flow Cytometry에 적합. HEK293T 세포에서 발현된 full-length human DTYMK 항원을 면역원으로 사용. 고순도 Affinity chromatography 정제, 안정한 PBS/BSA/glycerol buffer에 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C4 |
| Immunogen | Full-length human recombinant DTYMK protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.64 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and plays an important role as an intermediate enzyme in the metabolism of pyrimidine analog drugs such as 5-Fluorouracil (5-FU), a key chemotherapeutic agent for several solid tumors. The human DTYMK gene was identified through functional complementation of a Saccharomyces cerevisiae cell cycle mutant (cdc8). Expression of DTYMK mRNA and enzyme activity are regulated by cell cycle and growth pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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